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Highlights from the EAS 2018 Lisbon Opening Ceremony

Saturday 5 May 2018   (0 Comments)
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Inaugural Meeting in Lisbon – with a unique Portuguese flair...

Lisbon welcomed about 2000 delegates from across all continents at the Opening of the 86th Annual Congress of the European Atherosclerosis Society (EAS). EAS President Professor Lale Tokgözoğlu overviewed the past, present and ongoing activities of the Society. These include collaboration with the European Society of Cardiology in the production of guidelines, such as those for management of dyslipidaemia, as well as with international and national atherosclerosis societies.


Integral to the success of the EAS has been the European Atherosclerosis Society Consensus Panel, co-authored by Professor John Chapman (EAS Past President 2010-2013), Professor Henry Ginsberg (Columbia University, New York, USA) and Professor Alberico L. Catapano (EAS Past President 2014-2017). First founded in 2009, the Panel has now published nine papers in prestigious journals including the European Heart Journal, Lancet Diabetes Endocrinology, as well as the Society’s journal Atherosclerosis. The latest of these papers has evaluated statin adverse effects, specifically focusing on possible unintended effects on glucose homeostasis, cognitive, renal and hepatic function, as well as risk for haemorrhagic stroke or cataract.1 The key findings will be discussed at the Second Late Breaking Session on Monday 7th May, 15:45-17:00.

Another of the key EAS initiatives is the Familial Hypercholesterolaemia Studies Collaboration (FHSC), a global network- to date involving 65 countries and growing - of healthcare providers, patient organizations, policy makers and the clinical community. At this year’s Congress the first data from over 200 patients in the Homozygous Familial Hypercholesterolaemia International Clinical Collaboration (HICC) registry – the largest cohort to date - will be presented at a Science at a Glance session on Monday 7th May, 14:45-15:45. Other initiatives include the web-based EAS Academy, free to access with EAS membership.

2018 also sees the launch of the Young Fellows of EAS, an educational initiative which aims to recruit exciting young atherosclerosis researchers (both bench and clinical), with the ultimate aim of developing the next generation of Key Opinion Leaders.

Young Investigator Awards were presented to José Javier Fuster Ortuño, Boston University School of Medicine, Boston, USA for his research ‘Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice,’2 and Christian Medom Madsen, Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark for two publications: ‘Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies’ and ‘U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies.’3,4

EAS is continuing to build on its wealth of expertise, and importantly, is also looking to ensure the future success of the Society with the Young Fellows of EAS programme – EAS President Professor Tokgözoğlu.

Deputy Director of the Ministry of Health, Portugal, Dr. D Cruz, welcomed delegates: This is the first time that the EAS Congress has been held in Portugal. We welcome the opportunity to expand knowledge of atherosclerosis and cardiovascular disease in Portugal.

Congress Chair, Professor Alberto Mello e Silva, cardiologist and current Chair of the Portuguese Atherosclerosis Society, added that this year’s Congress will provide the latest current research in the field, as well as a programme of plenary, advanced clinical and workshop sessions featuring world renowned experts in the field. Not to mention two Key Note Lectures by two international experts: Professor Peter Libby, Brigham and Women’s Hospital and Harvard Medical School, Boston, USA and Emerita Professor Marja-Riitta Taskinen, University of Helsinki, Finland.

President of the International Atherosclerosis Society (IAS) Professor Yuji Matsuzawa congratulated the Congress Scientific Committee on a well-planned meeting. Recognizing the importance of collaboration between the societies, he highlighted the Joint IAS/EAS Session on ‘Genetics, metabolomics and cardiovascular risk factors’, on Sunday 6th May at 11:30.

Cardiovascular disease is one of the leading causes of death and disability globally. Ongoing collaborations between the EAS and IAS, as well as EAS initiatives, will undoubtedly provide important insights to address this world-wide burden.
– IAS President Professor Yuji Matsuzawa.


Portuguese fado was a fitting musical introduction to an exciting Congress in Lisbon in 2018.


References
1. François Mach, Kausik K. Ray, Olov Wiklund, Alberto Corsini, Alberico L. Catapano, Eric Bruckert, Guy De Backer, Robert A. Hegele, G. Kees Hovingh, Terry A. Jacobson, Ronald M. Krauss, Ulrich Laufs, Lawrence A. Leiter, Winfried März, Børge G. Nordestgaard, Frederick J. Raal, Michael Roden, Raul D. Santos, Evan A. Stein, Erik S. Stroes, Paul D. Thompson, Lale Tokgözoglu, Georgirene D. Vladutiu, Baris Gencer, Jane K. Stock, Henry N. Ginsberg, and M. John Chapman; European Atherosclerosis Society Consensus Panel. Adverse effects of statin therapy: perception vs. the evidence – focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract. European Heart Journal DOI: 10.1093/eurheartj/ehy182. First published online: 27 April 2018.

2. Fuster JJ, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu CL, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AA, Cooper MA, Andrés V, Hirschi KK, Martin KA, Walsh K. Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice. Science 201;355:842-847.

3. Madsen CM, Varbo A, Nordestgaard BG. Extreme high high-density lipoprotein cholesterol is paradoxically associated with high mortality in men and women: two prospective cohort studies. Euro Heart J 2017;38:2478–2486.

4. Madsen CM, Varbo A, Tybjærg-Hansen A, Frikke-Schmidt R, Nordestgaard BG. U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies. Eur Heart J 2018;39:1181–1190.


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