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News: EAS Academy

Open lecture November - December 2018

Monday 29 October 2018   (0 Comments)
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Introducing Featured Open Lectures

This is a new initiative from the Society to highlight our online educational platform EAS ACADEMY. Every other month we select one interesting lecture from a recent course or congress and make it available for free, to members and non-members.

Open Lecture November - December 2018

Plenary Lecture

This presentation was given as a plenary lecture entitled “Lessons from epidemiology and environmental CVD risk factors” by Professor Salim Yusuf.
Salim Yusuf is an internationally renowned cardiologist and epidemiologist whose
work over 35 years has substantially influenced prevention and treatment of cardiovascular disease. He is heading the Population Health Research Institute in Hamilton, Canada. 

In his plenary lecture Professor Yusuf gave an overview of cardiovascular disease (CVD) as among the leading causes of morbidity and premature mortality worldwide. INTERHEART, a case-control study involving 52 countries worldwide, demonstrated that nine risk factors – abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity – accounted for >90% of the population attributable risk for myocardial infarction (MI). There are however issues in analysis of the impact of different risk factors, given the possibility of confounding with multiple highly correlated factors. Thus, Professor Yusuf emphasized that the interpretation of epidemiological data requires caution. For example, both blood pressure and low-density lipoprotein cholesterol (LDL-C) show continuous graded associations with cardiovascular risk in observational studies. However only LDL-C seems to have no lower threshold for the relationship between absolute LDL-C reduction and absolute reduction in CVD events in clinical trials. Thus, it may be inappropriate to interpret the associated disease burden solely from observational data. Importantly, while there has been much progress in understanding global CVD epidemiology, gaps in evidence, especially in middle- and low-income countries, remains.

Free access to the lecture will be open until January 7, 2018.


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