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Ebo Derk de Muinck

Ebo Derk de Muinck was Born February 15, 1957 Rotterdam, the Netherlands (NL).


Non-invasive and invasive cardiology, NL.


Ph.D., Groningen, NL.


Assistant Professor, Maastricht, NL.


Assistant and Associate Professor, Dartmouth Medical School, USA.


Associate Professor, Linköping.


Professor of Vascular Biology, Linköping. Our interest is in developing magnetic resonance imaging (MRI) methods to detect rupture prone atherosclerotic plaque, improve cardiovascular risk management (CVRM) in patients with peripheral arterial disease and improve wound healing after myocardial infarction (MI). We have developed MRI methods for direct in vivo quantification of lipid rich necrotic core and intraplaque haemorrhage to identify rupture prone plaques. This method has been validated against histology in patients with CAS who undergo carotid endarterectomy (CEA). Regardless of whether these patients undergo CEA they have extensive cardiovascular co-morbidity and we have shown that their CVRM is suboptimal. Thus we are designing a nurse-led program aimed to improve self-care and CVRM in all patients with CAS. We have shown that depletion of inflammatory dendritic cells during post-MI healing significantly reduces inflammation in the MI wound leading to a significant reduction in MI size. I am actively involved in the development of this discovery into a therapeutic for MI patients.

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