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International Symposium HDL- Beyond Atherosclerosis
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International Symposium HDL- Beyond Atherosclerosis

When: Friday, February 01,
February 01, 2019
Where: University of Milan - La Statale Department of Pharmacological and Biomolecular Science
Via Balzaretti 9
Contact: Mr Massimiliano Ruscica

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The clinical utility of high density lipoproteins (HDL) in the prevention and treatment of atherosclerotic cardiovascular disease (ASCVD) has been scrutinized in recent years by the failures of randomized controlled intervention trials as well as the lack of association between HDL-Cholesterol modifying variants and ASCVD outcome.

HDL exert multiple functions that contribute to host defense from biological or chemical harm and mediate repair of tissue damage.
These protective functions make HDL interesting therapeutic targets beyond the management of ASCVD.
In fact recent epidemiological, clinical, genetic and experimental research indicate the involvement of HDL in many pathologies including diabetes, nephropathies, infections, chronic inflammatory diseases, cancers, and age-related macular degeneration.

Unravelling the molecular basis of these protective effects and associations may improve the management of these and other diseases. In addition, artificial HDL may be used for the delivery of tracers and drugs for imaging and targeted treatment. The one-day meeting aims to summarize the recent progress in this novel direction of HDL research.

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