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Young Investigator award

In 1998 the idea was launched to organise a Young Investigator Award. From 2004 and onwards we have also had a competition for the Young Investigator Poster Award. Since 2011 the awards have been named after the late Dr. Joachim-Ziegenhorn, in memory of his strong and persistent support of the ELC. The prize is a diploma and a financial reward which until recently was sponsored by the journal "Clinical Science".

Young Investigator award winners:

2016 Oral award winner Christian Medom Madsen (Copenhagen, Denmark)
Low concentrations of high-density lipoprotein cholesterol and high risk of infectious disease.

2016 Oral award winner Faiza Qayyum (Copenhagen, Denmark)
Genetic variation in CYP7A1, LDL cholesterol, myocardial infarction, and symptomatic gallstone disease.

2016 Poster award winner Sander Kooijman (Oxford, UK)
Familial longevity is characterized by preserved circadian rhythmicity of serum cholesterol levels in healthy middle-aged individuals

2015 Anders Berg Jørgensen (Copenhagen, Denmark)
Can the reduction in ischemic vascular disease in carriers of APOC3 loss-of-function mutations be explained by a reduction in LDL cholesterol levels?

2014 Kirstin Albers (Hamburg, Germany)
The LRP1 adaptor protein PID1 regulates glucose uptake into muscle and adipose tissues
(shared award)

2014 Alena Grebe (Bonn, Germany)
Cyclodextrin dissolves cholesterol crystals, mediates LXR gene expression and promotes atherosclerosis regression in mice.
(shared award)

2013 Birgit Plochenberger (Vienna, Austria)
HDL lipid uptake regulated by mechanical properties of the plasma membrane

2011 Alexander Bartelt (Hamburg, Germany)
From lipoprotein lipase to CD36: how brown adipose tissue controls vascular triglyceride metabolism

2010 Max Nieuwdorp (Amsterdam, The Netherlands)
Metabolic effects of transplantating gut microbiota from lean donors to subjects with metabolic syndrome

2009 Tanja Pedersen (Copenhagen, Denmark)
Osteopontin is Pivotal for Development of Uremic Atherosclerosis

2008 Christina Christofferson (Copenhagen, Denmark)
The signal peptide anchors apolipoprotein M in plasma lipoproteins and prevents rapid clearance of apolipoprotein M from plasma

2007 Oliver Bruns (Hamburg, Germany)
Non-invasive in Vivo Imaging of Recombinant TRL Labelled with Nanocrystals
2006 Malin Levin (San Francisco CA, United States)

Acyl CoA: Diacylglycerol Acyltransferase 2 (DGAT2)–Mediated Triacylglycerol Accumulation in Glycolytic Muscle Promotes Insulin Resistance
2005 Astrid van der Velde (Amsterdam, The Netherlands)

Unraveling of the Mechanisms Underlying the Intestinal Cholesterol Excretion Pathway
2012 Marietta Rebecca Boon (Leiden, The Netherlands)
BMP-7 reduces high fat diet-induced adiposity in mice by activating brown adipose tissue in sympathetic-dependent way

2004 Torsten Plösch (Groningen, The Netherlands)
Evidence for Abcg5-independent Hepatobiliary Cholesterol Secretion in Mice

2003 Arja Kreeft (Leiden, The Netherlands)
Identification of dietary response genes in hyperlipidemic mouse models by gene expression profiling.

2002 Menno de Winther (Maastricht, The Netherlands)
Inhibition of macrophage NF-kB activation enhances atherosclerosis in LDLR deficient mice.

2001 Garry Tan (Oxford, United Kingdom)
Subcutaneous adipose tissue function in a subject with a dominant negative PPAR-gamma mutation (PPAR-gamma-P467L).

2000 E. Peer Lutz (New York NY, United States)
Heparin-binding defective lipoprotein lipase (LpL): evidence that the carboxyl-terminal region affects LpL binding to cells, LpL removal from the bloodstream and plasma triglyceride removal.

1999 Walter Stockinger (Vienna, Austria)
Are members of the LDL receptor family involved in signaling events?

1998 Martin Raabe (San Francisco CA, United States)
The role of microsomal triglyceride transfer protein in yolk sac, liver, intestine,and heart assessed by gene knockout in mice.

Poster Awards

2015 Melinde Wijers (Groningen, The Netherlands)
The COMMD family of proteins forms a large protein complex to regulate the intracellular trafficking of LDLR

2014 Sander Kooijman (Leiden, The Netherlands)
Circadian Rhytm modulates body fat mass through brown adipose tissue activity

2013 Kirstin Albers (Hamburg, Germany)
Adaptor protein PID1 influences LRP1 function in liver and adipose tissue

2012 Laetitia Lichtenstein (Toulouse, France)
Decreased biliary lipid secretion in P2Y13/apoE double knock-out mice is coupled to an increase in atherosclerosis

2011 Andrea Dichlberger (Helsinki, Finland)
Arachidonic acid-induced Formation of Human Mast Cell Lipid Droplets is mediated by Long-chain Acyl-CoA Synthetases

2010 Marcela Aparicio-Vergara (Groningen, The Netherlands)
Hyperstimulation of TNFR1 and its role in hepatic steatosis

2009 Sophie Colin (Lille, France)
The Enterocyte: A Potential Target of PPARalpha Ligands to Control HDL metabolism

2008 Philip Gordts (Leuven, Belgium)
Inactivation of the NPxYxxL Motif of LRP1 Reduces Lipoprotein Clearance and Affects Adipogenesis.

2007 Philip Gordts (Leuven, Belgium)
Inactivation of the NPXYXXL Domain and Downstraem Motifs of LRP1 Show a Differential Increase in Atherosclerosis

2006 Willeke de Haan (Leiden, The Netherlands)
Torcetrapib Increases HDL by Inhibiting CETP Activity, while Atorvastatin Increases HDL by Reducing CETP Expression

2005 Guiseppe Norata (Milan, Italy)
High-density Lipoproteins Induce Transforming Growth Factor Beta 2 Expression in Endothelial Cells

2004 Susan Coort (Maastricht, The Netherlands)
Enhanced sacrolemmal FAT/CD36 content and tryacylglycerol storage in cardiac myocytes from obese Zucker rats

2004 Marisa Tschernatsch (Graz, Austria)
Implication of HuR in the regulation of mRNA-stability of genes relevant in lipid metabolism
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