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Sridevi Devaraj

Sridevi Devaraj is the Director of Chemistry and POCT at Texas Children’s Hospital, Professor of Pathology and Immunology at Baylor College of Medicine and Associate Director of the Texas Childrens Microbiome Center.

S. Devaraj, PhD graduated from the Post-Graduate Institute of Basic Medical Sciences, Madras, India, with a PhD in Biochemistry and thereafter undertook fellowships at the University of Texas Southwestern Medical Center, Dallas in Human Nutrition and Clinical Chemistry (1994-1997). In 1999 she became Assistant Professor of Clinical Biochemistry and Human Metabolism in the Department of Pathology at UT Southwestern. In 2002, she joined UC Davis as Assistant Professor in the Laboratory for Atherosclerosis and Metabolic Research and Director of Toxicology and Special Chemistry in the Department of Pathology at the University of California, Davis Medical Center in Sacramento, CA, where she quickly rose to the rank of Professor. Also, she served as the Laboratory Core Director of the General Clinical Research Center and Co-Director of the Translational Program at UCDavis Medical Center.In 2011, she moved to Texas Childrens Hospital and Baylor College of Medicine in Houston, TX. Presently, Dr. Devaraj is the Director of Chemistry and POCT at Texas Children’s Hospital, Professor of Pathology and Immunology at Baylor College of Medicine and Associate Director of the Texas Childrens Microbiome Center.

To date she has published over 250 original papers and invited reviews in the areas of clinical biochemistry, diabetes and atherosclerosis, metabolism, nutrition and free radical biology. She has received numerous awards for her work including the George Grannis Award from the National Academy Of Clinical Biochemistry and an award for Outstanding Achievements by a Young Investigator in Clinical Chemistry and Outstanding Contributions to Clinical Chemistry in Science and technology from the American Association Of Clinical Chemistry as well as the Merck Young Investigator Award in Atherosclerosis. She is presently a member of the American Association of Clinical Chemistry, National Academy of Clinical Biochemistry and the American Heart Association. She also serves as Chair-Elect of the Lipids and Lipoprotein Division of the AACC. She is on the Editorial Board of several journals including Atherosclerosis, Archives of Pathology and Laboratory Medicine, Clinica Chimica Acta, Metabolic Syndrome and Related Disorders, etc. Presently, her major research interests are atherosclerosis, inflammation, oxidative stress, antioxidants and diabetes and nutritional modulation of risk factors for heart disease. Her research has been funded by the NIH, ADA, AHA and other sponsors.

A list of her recent publications are:

  1. Yun JM, Chien A, Jialal I, Devaraj S. Resveratrol up-regulates SIRT1 and inhibits cellular oxidative stress in the diabetic milieu: mechanistic insights. J Nutr Biochem. 2011 Aug 1. [Epub ahead of print] PubMed PMID: 21813271.
  2. Jialal I, Devaraj S. Laboratory diagnosis of ethylene glycol poisoning: the cup is half full? Am J Clin Pathol. 2011 Aug;136(2):165-6..
  3. Devaraj S, Torok N. Leptin: The missing link between obesity and heart disease? Atherosclerosis. 2011 Aug;217(2):322-3.
  4. Devaraj S, Tobias P, Kasinath BS, Ramsamooj R, Afify A, Jialal I. Knockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathy. Arterioscler Thromb Vasc Biol. 2011 Aug;31(8):1796-804.
  5. Devaraj S, Tobias P, Jialal I. Knockout of toll-like receptor-4 attenuates the pro-inflammatory state of diabetes. Cytokine. 2011 Sep;55(3):441-5.
  6. Devaraj S, Jialal I, Rockwood J, Zak D. Effect of orange juice and beverage with phytosterols on cytokines and PAI-1 activity. Clin Nutr. 2011 Apr
  7. [Epub ahead of print] PubMed PMID: 21477901. 7: Devaraj S, Jialal I. C-reactive protein polarizes human macrophages to an M1 phenotype and inhibits transformation to the M2 phenotype. Arterioscler Thromb Vasc Biol. 2011 Jun;31(6):1397-402.
  8. Devaraj S, Yun JM, Duncan-Staley CR, Jialal I. Low vitamin D levels correlate with the proinflammatory state in type 1 diabetic subjects with and without microvascular complications. Am J Clin Pathol. 2011 Mar;135(3):429-33.
  9. Devaraj S, Jialal G, Cook T, Siegel D, Jialal I. Low vitamin D levels in Northern American adults with the metabolic syndrome. Horm Metab Res. 2011 Jan;43(1):72-4.
  10. Jialal I, Fadini GP, Pollock K, Devaraj S. Circulating levels of endothelial progenitor cell mobilizing factors in the metabolic syndrome. Am J Cardiol. 2010 Dec 1;106(11):1606-8.
  11. Devaraj S, Duncan-Staley C, Jialal I. Evaluation of a method for fibroblast growth factor-23: a novel biomarker of adverse outcomes in patients with renal disease. Metab Syndr Relat Disord. 2010 Dec;8(6):477-82.
  12. Yun JM, Jialal I, Devaraj S. Epigenetic regulation of high glucose-induced proinflammatory cytokine production in monocytes by curcumin. J Nutr Biochem. 2011 May;22(5):450-8.
  13. Devaraj S, Jialal I, Yun JM, Bremer A. Demonstration of increased toll-like receptor 2 and toll-like receptor 4 expression in monocytes of type 1 diabetes mellitus patients with microvascular complications. Metabolism. 2011 Feb;60(2):256-9.
  14. Devaraj S, Cheung AT, Jialal I, Griffen SC, Nguyen D, Glaser N, Aoki T. Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications. Diabetes. 2007 Nov;56(11):2790-6.

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